The Division of Well being and Human Companies (HHS) launched what it known as a “comprehensive review” of transgender care for kids and youths on Thursday, calling for broader use of psychotherapy for younger individuals with gender dysphoria quite than gender-affirming care.
The greater than 400-page doc particulars alleged harms from medical interventions for youth, together with using puberty blockers, and alleged dangers, corresponding to infertility.
The “evaluate of proof and finest practices report” is a response to a January executive order issued by President Donald Trump, saying the federal authorities wouldn’t “fund, sponsor, promote, help or assist” transition take care of these underneath age 19.
“Our obligation is to guard our nation’s youngsters — not expose them to unproven and irreversible medical interventions,” Dr. Jay Bhattacharya, director of the Nationwide Institutes of Well being, stated in a statement on Thursday. “We should comply with the gold commonplace of science, not activist agendas.”
Gender-affirming care is supported by a number of main medical organizations. It could vary from permitting a toddler to select their pronouns to remedies usually prescribed for older teenagers. Research present remedies are generally safe and that care has a optimistic influence on psychological well being, which psychotherapy alone can not present, consultants stated.
“Requiring that any individual [go] by way of a prescribed course of remedy will be misused by governments to attempt to basically block entry to care,” Dr. Dan Karasic, professor emeritus of psychiatry on the College of California San Francisco Weill Institute for Neurosciences, informed ABC Information. “There simply is not proof that psychotherapy resolves gender dysphoria.”
President Donald Trump holds an govt order referring to training within the Oval Workplace of the White Home, April 23, 2025.
Alex Brandon/AP
Security of puberty blockers, hormone therapies
Probably the most frequent remedies in gender-affirming care is using puberty blockers, that are used to delay the onset of puberty amongst transgender and gender-diverse youth.
The report claimed its evaluate of research discovered low proof that puberty blockers are protected or that they improved psychological well being amongst youngsters with gender dysphoria, and “excessive certainty proof” that they typically trigger infertility.
The reported additionally acknowledged, “Low certainty proof means that puberty blockers might compromise bone well being.”
Nevertheless, studies have shown that adults who used puberty blockers up to now skilled menstrual cycles, childbirth and miscarriages at comparable charges to these of the final inhabitants.
Dr. Morissa Ladinsky, a medical professor in pediatrics at Stanford College in California, stated puberty blockers have been used as a remedy for greater than 30 years, primarily for a situation known as CPP, or central precocious puberty, which is when puberty begins too early.
“These medicines are immensely well-studied,” she informed ABC Information. “The long-term results of puberty-pausing medicines, when utilized in youngsters, for short-term durations of time, do operate as a very reversible pause button.”
She stated unwanted side effects associated to sexual operate or bone density are normally seen amongst adults, who might take the medicines for prostate most cancers in an effort to cut back testosterone, or endometriosis.
The HHS report additionally mentioned cross-sex hormones, extra generally generally known as hormone therapies, claiming there may be “excessive certainty proof” that hormone therapies have “physiological results” and that many research have been “not particularly designed to seize the complete vary of long-term outcomes.”
Though hormones can carry unwanted side effects, like several drugs, they’ll greatly improve the mental health of these with gender dysphoria, research present.

Signage for the Division of Well being and Human Companies (HHS) headquarters is seen, April 2, 2025, in Washington, D.C.
Anna Moneymaker/Getty Photos
Ladinsky stated hormone therapies are sometimes used with older adolescents who’ve had sustained gender dysphoria over a protracted time period.
Hormone therapies “are all used and have been utilized in pediatric and adolescent drugs, for a protracted, lengthy, very long time,” she stated. “Any one that’s ever used mixture contraception tablets has taken oral estrogen. So, it isn’t that these medicines are distinctive, experimental, pulled off a shelf. They’re commonplace pharmacology within the apply of medication.”
Controversy round surgical procedures
The evaluate stated it discovered three research on surgical procedures for kids or adolescents with gender dysphoria “with most contemplating mastectomy solely.”
Gender-affirming mastectomy, identified colloquially as “high surgical procedure,” is a surgical process that removes breast tissue to create a extra masculine-looking chest.
The report stated authors discovered low certainty of proof on the consequences of gender-affirming surgical procedures on adolescents together with suicidality, melancholy, asexual operate, high quality of life and remorse.
Ladinsky stated there aren’t any gender-affirming genital surgical procedures that happen on minors and no different gender-affirming surgical procedures being carried out on younger youngsters.
“There’s a very small group of trans-masculine older teenagers, that means 17-ish, 18, who — in our evidence-based, guideline-driven commonplace of care — does permit for a tiny group of those older trans-masculine teenagers with overwhelming and sustained gender dysphoria to have masculinizing chest surgical procedure,” she stated.
Ladinsky continued, “That may be very, very uncommon and that process can solely be executed with lengthy durations of oversight round gender dysphoria with medical doctors, immense parental consent {and professional} endorsement by these caring for the younger individual.”
HHS advocates for psychotherapy
The HHS report advocates for using psychotherapy as a remedy for kids and adolescents with gender dysphoria.
“Psychotherapy is a noninvasive different to endocrine and surgical interventions for the remedy of pediatric gender dysphoria,” the report acknowledged. “Systematic evaluations of proof have discovered no proof of antagonistic results of psychotherapy on this context.”

Dr. Klara Widrig protests with fellow activists throughout the Trans Day Of Visibility rally on the Nationwide Mall, March 31, 2025, in Washington, D.C.
Kayla Bartkowski/Getty Photos
Karasic stated sure sorts of psychotherapy can be utilized to deal with signs of tension and melancholy amongst each cisgender and transgender people, however psychotherapy shouldn’t be thought-about an alternative choice to gender-affirming care.
“There’s completely no proof that psychotherapy is an alternative choice to these individuals who want medical care,” he informed ABC Information. “There’s substantial proof for the advantages of [gender-affirming] take care of minors, and that is why all mainstream medical and psychological well being teams assist this versus no proof of psychotherapy being a substitute.”
Karasic stated psychotherapy is just not dangerous, however quite that it has its place and, fairly often, youngsters and youngsters obtain psychotherapy together with medical intervention.
“If persons are proposing the provision of remedy for individuals who want it, I feel everybody would agree with that,” he stated. “However when persons are saying that medical intervention shouldn’t be supplied as a result of remedy can be utilized as a substitute, that is improper. There’s simply no proof to assist that.”
Response from the medical neighborhood
The American Academy of Pediatrics launched a statement on Thursday saying it’s “deeply alarmed” by the HHS report.
“For such an evaluation to hold credibility, it should contemplate the totality of obtainable information and the complete spectrum of medical outcomes quite than counting on choose views and a slim set of information,” the assertion learn partly. “This report misrepresents the present medical consensus and fails to replicate the realities of pediatric care.”
AAP additionally launched a statement with a number of teams, together with the American Academy of Household Physicians, the American School of Obstetricians and Gynecologists, the American School of Physicians, the American Osteopathic Affiliation and the American Psychiatric Affiliation, opposing an infringement on medical care.
“Our organizations have persistently opposed any laws, regulation or govt motion that interferes within the confidential relationship between a affected person and their doctor or undermines the availability of evidence-based requirements of affected person care and doctor coaching and training,” the assertion, launched on Thursday, learn. “Sufferers should should have the ability to focus on well being points with their trusted doctor to find out collectively what care is finest for them.”
Greater than 500 anti-LGBTQ+ payments have been launched all through the 2024 legislative session, in accordance with the American Civil Liberties Union.
Ladinsky stated these payments are dangerous they usually do not resolve gender dysphoria for anybody.
“If government-sanctioned, blatant misinformation is utilized to make coverage selections that have an effect on tens of millions of Individuals, we’re opening a Pandora’s field to drastically diminish the well being of all individuals, quite than elevating it,” she stated. “The opposite factor essential is that we all know from 25 states which have rendered unlawful components of this care, it hasn’t made any youngsters of trans id not trans.”